Anti-Y14/RBM8A Antibody, clone 5K5E6, Rabbit Monoclonal,100UL,SAB5702192-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BM4629
品牌型号 Sigma SAB5702192-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Y14/RBM8A (Q9Y5S9).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone5K5E6, monoclonal
formliquid
mol wt 20 kDa
species reactivityhuman, rat
concentration1.12 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIK
UniProt accession no.Q9Y5S9
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... RBM8A(9939)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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