Anti-NKX2-1 Antibody, clone 3O2N3, Rabbit Monoclonal，100UL，SAB5702957-100UL，Sigma

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订货号： 0BM5289

品牌型号： Sigma SAB5702957-100UL

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最小订货量： 1件

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产品介绍 Product Description

General description

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NKX2-1 (P43699).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
material	colorless
clone	3O2N3, monoclonal
form	liquid
mol wt	42 kDa
species reactivity	rat, human
concentration	0.33 mg/mL
technique(s)	immunofluorescence: 1:50 - 1:200,immunohistochemistry: 1:500 - 1:1000,western blot: 1:500 - 1:2000
color	colorless
isotype	IgG
immunogen sequence	MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPY
UniProt accession no.	P43699
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... NKX2-1(7080)

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