Anti-Oncostatin M Antibody, clone 8O8K9, Rabbit Monoclonal,100UL,SAB5702611-100UL,Sigma

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订货号 0BM5788
品牌型号 Sigma SAB5702611-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Oncostatin M (P13725).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IF/ICC


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone8O8K9, monoclonal
formliquid
mol wt 21 kDa
species reactivityrat, human
concentration0.40 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLN
UniProt accession no.P13725
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... OSM(5008)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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