Anti-KRAS+HRAS+NRAS Antibody, clone 6S6F3, Rabbit Monoclonal,100UL,SAB5702859-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BM6720
品牌型号 Sigma SAB5702859-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NRAS (P01111).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IF/ICC


技术参数 Specifications
biological sourcerabbit
Quality Level100
materialcolorless
clone6S6F3, monoclonal
formliquid
mol wt 20 kDa
species reactivityhuman, rat
concentration0.30 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI
UniProt accession no.P01111,P01112,P01116_
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... NRAS(4893)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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