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General description
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Immunogen
A synthesized peptide derived from human Phospho-S6K1 (T421 + S424).
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
| biological source | rabbit |
| Quality Level | 100 |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | rat, mouse, human |
| concentration | 0.5 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| UniProt accession no. | P23443 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr421/pSer242) |
| Gene Information | human ... RPS6KB1(6198) |
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¥ 4164.19
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