- 商品介绍
- 规格参数
- 包装参数
General description
Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2–11q23.3.
Immunogen
Synthetic peptide corresponding to Phospho-Histone H2AX (Ser139)
Biochem/physiol Actions
H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.
This antibody reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| recombinant | expressed in HEK 293 cells |
| Quality Level | 100 |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | RM224, monoclonal,recombinant monoclonal |
| form | buffered aqueous glycerol solution |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 0.2- 1 μg/mL,immunoblotting: 0.5-2 μg/mL,immunocytochemistry: 0.5-2 μg/mL |
| isotype | IgG |
| NCBI accession no. | 3014 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer139) |
| Gene Information | human ... H2AX(3014) |
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