Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse，0.2ML，P8087-.2ML，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .

Immunogen

recombinant chicken plakoglobin.

Application

Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).

Biochem/physiol Actions

The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Level	200
conjugate	unconjugated
antibody form	ascites fluid
antibody product type	primary antibodies
clone	15F11, monoclonal
form	buffered aqueous solution
mol wt	antigen 85 kDa
contains	15 mM sodium azide
species reactivity	bovine, canine, human
technique(s)	immunocytochemistry: suitable using cultured cells,immunohistochemistry (frozen sections): suitable,immunoprecipitation (IP): suitable,indirect immunofluorescence: 1:1,000 using cultured MDBK cells,microarray: suitable,western blot: 1:2,000 using cultured MDBK cells
isotype	IgG1
UniProt accession no.	P14923
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... JUP(3728)

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