Monoclonal Anti-PRELP antibody produced in mouse,200UL,SAB1402879-200UL,Sigma

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订货号 0BN0607
品牌型号 Sigma SAB1402879-200UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. (provided by RefSeq)


Immunogen

PRELP (NP_002716.1, 281 a.a. ~ 365 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
RGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPP


Physical form

Clear solution


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formascites fluid
antibody product typeprimary antibodies
clone3H1, monoclonal
mol wtantigen ~35.46 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1:500-1:1000
isotypeIgMκ
NCBI accession no.NM_002725
UniProt accession no.P51888
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PRELP(5549)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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