- 商品介绍
- 规格参数
- 包装参数
General description
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Immunogen
A synthetic phosphorylated peptide around S345 of human CHEK1 (NP_001265.2).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Level | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 43, 50, 54 |
| species reactivity | human, mouse, rat |
| concentration | 1.27 mg/ml |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | O14757 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer345) |
| Gene Information | human ... CHEK1(1111) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 5167.58
-
瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
-
¥ 4404.38
-
¥ 2617.87
-
¥ 2307.00
-
¥ 4011.97
-
¥ 5014.59
-
¥ 4020.77
-
¥ 1783.21
-
¥ 2406.69
-
¥ 1351.48
-
¥ 4614.63
-
询价
-
询价
微信小程序
7X24小时在线咨询