- 商品介绍
- 规格参数
- 包装参数
Application
Useful for acetyltransferase assay.
Biochem/physiol Actions
Full-length recombinant human KAT5 was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. KAT5 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). KAT5 was originally isolated as an HIV-1 TAT-interactive protein that plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins (1). KAT5 protein is a histone acetylase that is involved in DNA repair and apoptosis and plays an important role in signal transduction. KAT5 acts as a cofactor of TAT that is involved in the regulation of HIV gene expression. KAT5 is also a co-regulator of transcription factors that either promote or suppress tumorigenesis (2).
Preparation Note
Formulated in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.
Store in aliquots at -70°C. Avoid freeze/thaw cycles.
| recombinant | expressed in baculovirus infected Sf9 cells |
| assay | 70-95% (SDS-PAGE) |
| form | frozen liquid |
| specific activity | 25-35 nmol/min·mg (radiometric) |
| mol wt | ~88 kDa |
| concentration | 0.1 μg/μL |
| accession no. | NM_006388 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... KAT5(10524) |
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¥ 1563.36
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¥ 1302.89
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¥ 9207.92
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¥ 1956.41
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¥ 5167.58
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¥ 15214.65
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