Monoclonal Anti-Cytokeratin 19 FITC produced in mouse，，SAB4702006-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.

Immunogen

MCF-7 human breast adenocarcinoma cell line

Biochem/physiol Actions

The mouse monoclonal antibody A53-B/A2 recognizes the rod domain of cytokeratin 19 (40 kDa), an intracellular antigen constituting intermmediate cytoskeleton filaments. Cytokeratin 19 is not expressed in hepatocytes; it is often co-expressed with cytokeratin 7.

Physical form

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preparation Note

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

技术参数 Specifications

conjugate	FITC conjugate
Quality Level	100
antibody product type	primary antibodies
clone	A53-B/A2, monoclonal
form	buffered aqueous solution
species reactivity	human
concentration	1 mg/ml
technique(s)	flow cytometry: suitable
isotype	IgG2a
UniProt accession no.	P08727
storage temp.	2-8°C
target post-translational modification	unmodified
Gene Information	human ... KRT19(3880)

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