Anti-MICA Antibody, clone 5A1P3, Rabbit Monoclonal,100UL,SAB5702139-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BN2204
品牌型号 Sigma SAB5702139-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MICA (Q29983).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone5A1P3, monoclonal
formliquid
species reactivityhuman, rat
concentration0.666 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEW
UniProt accession no.Q29983
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... MICA(100507436)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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