Monoclonal Anti-TLR2 antibody produced in mouse,100UG,SAB1409745-100UG,Sigma

销售价: ¥ 4585.89 / 件
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订货号 0BN3691
品牌型号 Sigma SAB1409745-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. (provided by RefSeq)


Immunogen

TLR2 (AAH33756.1, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDV


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2A3, monoclonal
formbuffered aqueous solution
mol wtantigen 36.63 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable
isotypeIgG2aκ
NCBI accession no.BC033756
UniProt accession no.O60603
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TLR2(7097)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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