小鼠Lepr / Leptin受体ELISA试剂盒,96WELLS,RAB0820-1KT,Sigma

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订货号 0BN3999
品牌型号 Sigma RAB0820-1KT
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The antibody pair provided in this kit recognizes mouse Leptin Receptor.


Application

请参考Protocol了解详情。


Biochem/physiol Actions

Leptin receptor (Lepr) belonging to class I cytokine receptor family, binds with leptin, a small non-glycosylated peptide hormone and transduces signal. Lepr expression is present in brain and immune cells. Signal transduction through Lepr regulates fat metabolism in mammals. Lepr is part of the hematopoietic pathway. Lepr is a marker for mesenchymal stem/stromal cells (MSCs) and regulates the regenerative process of bone and cartilage after injury. Lepr regulates pancreatic β cell functions. Polymorphism in Lepr causes metabolic diseases like obesity, dyslipidemia, hypertension and Type 2 diabetes. Mutations in Lepr associates with polycystic ovarian syndrome (PCOS) susceptibility.


技术参数 Specifications
species reactivitymouse
packagingkit of 96 wells (12 strips x 8 wells)
technique(s)ELISA: suitable
inputsample type cell culture supernatant(s)
sample type serum
sample type plasma
assay rangeinter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 32 pg/mL
standard curve range: 32.77-8000 pg/mL
detection methodcolorimetric
shipped inwet ice
storage temp.−20°C
Gene Informationmouse ... Lepr(16847)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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