- 商品介绍
- 规格参数
- 包装参数
General description
Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.
Immunogen
QDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRG
Biochem/physiol Actions
SILu™Lite IFNG is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 138 amino acids Expressed in human 293 cells, with a calculated molecular mass of 17 kDa. SILu Lite IFNG is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Lyophilized from a solution of phosphate buffered saline.
Legal Information
SILu is a trademark of Sigma-Aldrich Co. LLC
| biological source | human |
| Quality Level | 200 |
| recombinant | expressed in HEK 293 cells |
| assay | ≥98% (SDS-PAGE) |
| form | lyophilized powder |
| potency | ≥98% Heavy amino acids incorporation efficiency by MS |
| mol wt | calculated mol wt 17 kDa |
| technique(s) | mass spectrometry (MS): suitable |
| suitability | suitable for mass spectrometry (internal calibrator) |
| UniProt accession no. | P01579 |
| storage temp. | −20°C |
| Gene Information | human ... IFNG(3458) |
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¥ 1563.36
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¥ 1451.54
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¥ 3109.49
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¥ 4173.75
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¥ 1564.00
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