Monoclonal Anti-APOC3, (C-terminal) antibody produced in mouse，100UG，SAB1402692-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Apolipoprotein C3 (APOC3) is a 79 amino acid protein with a molecular weight of 8.8kDa. It is present on high density, low density and triglyceride-rich lipoproteins. The gene encoding this protein is localized on human chromosome 11q23.3.

Immunogen

APOC3 (NP_000031.1, 21 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SEAEDASLLSFMQGYMKHATKTAKDALSSVQESQVAQQARGWVTDGFSSLKDYWSTVKDKFSEFWDLDPEVRPTSAVAA

Biochem/physiol Actions

Apolipoprotein C3 (APOC3) is involved in the metabolism of triglyceride-rich lipoproteins. It may have a role in atherosclerosis. The protein stimulates hypertriglyceridemia (HTG) by inhibiting the activity of lipoprotein lipase and interfering with the binding of APOB or APOE to hepatic receptors. It also promotes very low density lipoprotein (VLDL) assembly and secretion in the liver.

Physical form

Solution in phosphate buffered saline, pH 7.4

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Level	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	8H7, monoclonal
form	buffered aqueous solution
mol wt	antigen ~34.8 kDa
species reactivity	human
technique(s)	immunofluorescence: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotype	IgG2aκ
NCBI accession no.	NM_000040
UniProt accession no.	P02656
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... APOC3(345)

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