- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.
Physical form
Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18
Analysis Note
The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.
| biological source | rat |
| Quality Level | 200 |
| recombinant | expressed in E. coli |
| assay | >97% (SDS-PAGE) |
| form | lyophilized powder |
| potency | 10-60 ng/mL ED50 |
| mol wt | predicted mol wt ~18.4 kDa |
| packaging | pkg of 25 μg |
| impurities | endotoxin, tested |
| UniProt accession no. | Q16552 |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | rat ... Il18(29197) |
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