Anti-HP1 gamma/CBX3 antibody produced in rabbit,100UL,SAB5701515-100UL,Sigma

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订货号 0BN4958
品牌型号 Sigma SAB5701515-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]


Immunogen

A synthesized peptide derived from human HP1 gamma/CBX3


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, rat, mouse
concentration1 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q13185
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CBX3(11335)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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