Anti-CD68 Antibody, clone 5S2F7, Rabbit Monoclonal,100UL,SAB5702269-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BN5840
品牌型号 Sigma SAB5702269-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD68 (NP_001242.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.


Application

WB, FC


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone5S2F7, monoclonal
formliquid
mol wt 80-130 kDa
species reactivityhuman, rat
concentration1 mg/mL
technique(s)flow cytometry: 1:50 - 1:200,western blot: 1:500 - 1:1000
color colorless
isotypeIgG
immunogen sequenceTSQGPSTATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNK
UniProt accession no.P34810
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CD68(968)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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