- 商品介绍
- 规格参数
- 包装参数
General description
PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.
Immunogen
PRKAG1 (AAKG_HUMAN, 270-306)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PRKAG1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | human, mouse |
| technique(s) | immunohistochemistry: 1:50-1:100,indirect ELISA: 1:1000,western blot: 1:100-1:500 |
| NCBI accession no. | NP_002724 |
| UniProt accession no. | P54619 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... PRKAG1(5571) |
| 长度(mm) | |
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¥ 1573.49
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¥ 2019.57
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¥ 1779.22
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¥ 2068.25
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¥ 2268.97
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¥ 2842.54
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¥ 3404.94
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¥ 2452.91
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¥ 954.17
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¥ 2173.94
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