Anti-phospho-p38 MAPK (pTyr³²²) antibody produced in rabbit，100UG，SAB4504094-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

MAPK14 (mitogen-activated protein kinase 14) is a Ser/Thr kinase made of 90 to 360 residues. p38αMAPK is ubiquitously expressed. It is found in the cytosol, but it can translocate to the nucleus. This gene is located on human chromosome 6p21.31.

Immunogen

The antiserum was produced against synthesized peptide derived from human p38 MAPK around the phosphorylation site of Tyr322.

Immunogen Range: 288-337

Biochem/physiol Actions

MAPK14 (mitogen-activated protein kinase 14) participates in resistance of colon cancer cells to camptothecin-related drugs. This protein is required for the growth of embryos. This gene controls proliferation, differentiation, cell death, adhesion, migration, as well as the response to stress and many metabolic pathways. Polymorphism in MAPK14/p38a leads to deletion or overproduction of myelosuppressive cytokines and result in certain bone marrow failure syndromes.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	antigen 41 kDa
species reactivity	mouse, rat, human
concentration	~1 mg/mL
technique(s)	ELISA: 1:5000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000
NCBI accession no.	Q16539
UniProt accession no.	Q16539
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	phosphorylation (pTyr322)
Gene Information	human ... MAPK14(1432)

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