Monoclonal Anti-GPRC5D antibody produced in mouse,100UG,WH0055507M1-100UG,Sigma

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订货号 0BN7076
品牌型号 Sigma WH0055507M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

G protein-coupled receptor 5D (GPRC5D), a surface receptor consists of seven putative transmembrane segments. It is expressed in the cell membrane. This protein belongs to the retinoic acid inducible gene 1 or retinoic acid inducible GPCR 1 (RAIG1) family. GPRC5D is located on human chromosome 12p13.


Immunogen

GPRC5D (NP_061124, 261 a.a. ~ 345 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
ELCILYRSCRQECPLQGNACPVTAYQHSFQVENQELSRARDSDGAEEDVALTSYGTPIQPQTVDPTQECFIPQAKLSPQQDAGGV


Biochem/physiol Actions

G protein-coupled receptor 5D (GPRC5D) considered as an important marker for monitoring the tumor load and also to target multiple myeloma cells. Overexpression of GPRC5D affects the expression of hard keratins and also decrease the metabolic activities of hair bulb cells (HBCs).


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone6D9, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2bκ
GenBank accession no.NM_018654
UniProt accession no.Q9NZD1
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GPRC5D(55507)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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