Anti-WWP1 antibody produced in rabbit,100UL,SAB2102717-100UL,Sigma

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订货号 0BN7204
品牌型号 Sigma SAB2102717-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Immunogen

Synthetic peptide directed towards the N terminal region of human WWP1


Biochem/physiol Actions

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. WWP1 is a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WWP1 belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.


Other Notes

Synthetic peptide located within the following region: ATASPRSDTSNNHSGRLQLQVTVSSAKLKRKKNWFGTAIYTEVVVDGEIT


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 105 kDa
species reactivitydog, bovine, rat, rabbit, human
concentration0.5 mg - 1 mg/mL
technique(s)immunohistochemistry: suitable,western blot: suitable
UniProt accession no.Q9H0M0
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... WWP1(11059)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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