Anti-APBA1/MINT1 antibody produced in goat,100UG,SAB2500073-100UG,Sigma

销售价: ¥ 4585.89 / 件
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订货号 0BN7346
品牌型号 Sigma SAB2500073-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) is a neuronal adaptor protein belonging to the X11 family. It consists of a centrally located phosphotyrosine binding domain which inhibits the production of Aβ peptide, two C-terminal postsynaptic density-95, large discs, zona occludens 1 (PDZ) domains.


Immunogen

Peptide with sequence C-EASHPSQDGKRQYK from the internal region of the protein sequence according to NP_001154.2.


Application

Anti-APBA1/MINT1 antibody produced in goat is suitable for indirect ELISA and western blot analysis.


Biochem/physiol Actions

APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) stabilizes amyloid precursor protein (APP) by directly interacting with it. It also restricts production as well as accumulation of proteolytic APP fragment in the brain of Alzheimer′s disease patients. It also suppresses glycogen synthase kinase-3β promoter activity by coupling with a silencer binding protein.


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.


技术参数 Specifications
biological sourcegoat
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivitymouse, human, rat
technique(s)indirect ELISA: suitable,western blot: suitable
UniProt accession no.Q02410
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... APBA1(320)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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