(S)-GSK2920487A,5MG,SML3193-5MG,Sigma

销售价: ¥ 1200.47 / 件
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订货号 0BN7454
品牌型号 Sigma SML3193-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

(S)-GSK2920487A is a promising anti-leishmanial agent that potently and specifically inhibits oxidosqualene cyclase (OSC) of Leishmania donovani. (S)-GSK2920487A induces the accumulation of the 2,3-oxidosqualene, a substrate of OSC, in promastigotes and cell-free membrane preparations. It is active against axenic and intramacrophage amastigotes. Also, GSK2920487A is active against intracellular T. cruzi.
promising anti-leishmanial agent that potently and specifically inhibits oxidosqualene cyclase (OSC) of Leishmania donovani


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
color white to gray
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
SMILES stringO=C(N1C[C@H](CCC1)N2C=CN=C2C)C3=CC4=C(S3)C=CC=C4F
InChI1S/C18H18FN3OS/c1-12-20-7-9-22(12)13-4-3-8-21(11-13)18(23)17-10-14-15(19)5-2-6-16(14)24-17/h2,5-7,9-10,13H,3-4,8,11H2,1H3/t13-/m0/s1
InChI keySBZYUUGJHIROPT-ZDUSSCGKSA-N
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