- 商品介绍
- 规格参数
- 包装参数
General description
RIPK5 is a dual specificity serine/threonine and tyrosine protein kinase that is a member of the RIPK family. RIPK5 is widely expressed in vertebrates with broad distributed in the central nervous system, and deregulated in certain human cancers. RIPK5 has been shown to function as a regulator of cell death. Overexpression of RIPK5 leads to cell death as evidenced by DNA fragmentation. RIPK5 induces both caspase-dependent and caspase-independent cell death, and N- and C-terminal RIPK5 deletion mutants retained the ability to induce cell death.
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 5-7 nmol/min·mg |
| mol wt | ~140 kDa |
| NCBI accession no. | NM_015375 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... DSTYK(25778) |
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¥ 2068.25
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¥ 5887.85
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¥ 4897.21
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¥ 14407.09
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¥ 20380.83
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¥ 745.60
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¥ 5014.59
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¥ 44224.19
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¥ 26022.64
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