CHK1, active, GST tagged human,10UG,C0870-10UG,Sigma

销售价: ¥ 5184.97 / 件
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订货号 0BN8779
品牌型号 Sigma C0870-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

CHK1 is a 56 kDa serine/threonine protein kinase that was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle. CHK1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by rad3+, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
Quality Level200
product linePRECISIO® Kinase
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity169-229 nmol/min·mg
mol wt ~82 kDa
UniProt accession no.O14757
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... CHEK1(1111)
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