Anti-Phospho-Bad-S136 antibody produced in rabbit,100UL,SAB5700282-100UL,Sigma

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订货号 0BN8891
品牌型号 Sigma SAB5700282-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.


Immunogen

A phospho specific peptide corresponding to residues surrounding S136 of human Bad


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 18
species reactivitymouse, human
concentration2.05 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q92934
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pSer136)
Gene Informationhuman ... BAD(572)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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