IL-36α mouse,10UG,SRP8035-10UG,Sigma

销售价: ¥ 3733.94 / 件
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订货号 0BN9563
品牌型号 Sigma SRP8035-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.


Physical form

Lyophilized from PBS.


Preparation Note

Reconstitute with 100 μL deionized water.


Other Notes

IL-36alpha (mouse) (aa 8-160) is untagged.


技术参数 Specifications
biological sourcemouse
recombinantexpressed in E. coli
conjugateuntagged
assay>95% (SDS-PAGE)
formlyophilized
mol wt ~17 kDa
packagingpkg of 10 μg
impurities<0.01 EU/μg endotoxin, tested
UniProt accession no.Q9JLA2
shipped inwet ice
storage temp.−20°C
Gene Informationmouse ... Il36a(54448)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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