Anti-Phospho-PDGFR beta-Y751 antibody produced in rabbit,100UL,SAB5700369-100UL,Sigma

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订货号 0BN9832
品牌型号 Sigma SAB5700369-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.


Immunogen

A synthetic phosphorylated peptide around Y751 of human PDGFR beta (NP_002600.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 123, 37
species reactivityhuman, mouse
concentration1.73 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.P09619
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pTyr751)
Gene Informationhuman ... PDGFRB(5159)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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