Anti-Integrin alpha 5 (ITGA5/CD49e) Antibody, clone 8F2O6, Rabbit Monoclonal,100UL,SAB5702099-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BP0216
品牌型号 Sigma SAB5702099-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 950-1049 of human Integrin alpha 5 (ITGA5/CD49e) (P08648).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IHC, IF/ICC, IP, FC


技术参数 Specifications
biological sourcerabbit
Quality Level100
materialcolorless
clone8F2O6, monoclonal
formliquid
species reactivityhuman, rat
concentration0.44 mg/mL
technique(s)flow cytometry: 1:50 - 1:200,immunofluorescence: 1:50 - 1:200,immunohistochemistry: 1:50 - 1:200,immunoprecipitation (IP): 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA
UniProt accession no.P08648
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ITGA5(3678)
长度(mm)
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重量(kg)
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