- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
IRAK2 (interleukin-1 receptor-associated kinase 2) belongs to the IRAK family and is ubiquitously expressed. The protein contains an amino terminal death domain and a central kinase domain. IRAK2 is required for TLR (Toll-like receptor) signaling. Upon activation of TLR4 and TLR8, IRAK2 is crucial for the induction of TNF (tumor necrosis factor). It also regulates endoplasmic reticulum stress signaling.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Level | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 5-7 nmol/min·mg |
| mol wt | ~103 kDa |
| UniProt accession no. | O43187 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... IRAK2(3656) |
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| 重量(kg) |
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¥ 2528.88
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¥ 1596.77
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¥ 2013.69
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¥ 1302.89
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¥ 3109.49
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¥ 5887.85
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¥ 15214.65
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¥ 14407.09
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¥ 1783.21
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¥ 2277.64
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¥ 5804.96
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¥ 4476.05
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