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Anti-p63 Antibody, clone 3M9X7, Rabbit Monoclonal，100UL，SAB5702933-100UL，Sigma

销售价： ¥ 3636.13 / 件

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订货号： 0BP2031

品牌型号： Sigma SAB5702933-100UL

货期：询货期

最小订货量： 1件

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产品介绍 Product Description

General description

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human p63 (Q9H3D4).

Application

WB, IHC

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
material	colorless
clone	3M9X7, monoclonal
form	liquid
mol wt	52-68 kDa
species reactivity	mouse
concentration	1.55 mg/mL
technique(s)	immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000
color	colorless
isotype	IgG
immunogen sequence	MNFETSRCATLQYCPDPYIQRFVETPAHFSWKESYYRSTMSQSTQTNEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYC
UniProt accession no.	Q9H3D4
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... TP63(8626)

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