- 商品介绍
- 规格参数
- 包装参数
General description
Growth and differentiation factor-associated serum protein-1 (GASP-1) is expressed primarily in the ovary, testis, and brain. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66kDa by SDS-PAGE analysis under non-reducing conditions.
Biochem/physiol Actions
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-β binding protein that contains multiple protease inhibitor structural domains. It can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A.
Physical form
Lyophilized from 10 mM Sodium Phosphate, pH 7.8.
Preparation Note
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
| biological source | human |
| recombinant | expressed in CHO cells |
| assay | ≥95% (HPLC),≥95% (SDS-PAGE) |
| form | lyophilized |
| mol wt | 55.0-66.0 kDa |
| packaging | pkg of 25 μg |
| concentration | 0.0025-0.0040 μg/mL |
| impurities | <0.1 EU/μg endotoxin, tested |
| color | white to off-white |
| UniProt accession no. | Q8TEU8 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... WFIKKN2(124857) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |




微信小程序
7X24小时在线咨询