人 GASP-1,25UG,SRP3284-25UG,Sigma

销售价: ¥ 2612.12 / 件
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订货号 0BP2254
品牌型号 Sigma SRP3284-25UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Growth and differentiation factor-associated serum protein-1 (GASP-1) is expressed primarily in the ovary, testis, and brain. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66kDa by SDS-PAGE analysis under non-reducing conditions.


Biochem/physiol Actions

Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-β binding protein that contains multiple protease inhibitor structural domains. It can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A.


Physical form

Lyophilized from 10 mM Sodium Phosphate, pH 7.8.


Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.


技术参数 Specifications
biological sourcehuman
recombinantexpressed in CHO cells
assay≥95% (HPLC),≥95% (SDS-PAGE)
formlyophilized
mol wt 55.0-66.0 kDa
packagingpkg of 25 μg
concentration0.0025-0.0040 μg/mL
impurities<0.1 EU/μg endotoxin, tested
color white to off-white
UniProt accession no.Q8TEU8
shipped inwet ice
storage temp.−20°C
Gene Informationhuman ... WFIKKN2(124857)
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