- 商品介绍
- 规格参数
- 包装参数
General description
NADPH oxidase 1 (NOX1) is encoded by the gene mapped to human chromosome Xq22.1. The protein belongs to the family of NADPH oxidases and is co-localized with caveolin in punctate patches on the surface and laterally on the cellular margins. NOX1 is mainly expressed in colon epithelium.
Immunogen
Peptide with sequence C-DKATDIVTGLKQK, from the internal region of the protein sequence according toNP_008983.2; NP_39249.1
Application
Anti-NOX1 antibody produced in goat has been used for Western blotting.
Biochem/physiol Actions
NOX1 catalyzes the production of hydrogen peroxide (H2O2). Overexpression of the protein leads to the production of superoxide and H2O2 and triggers angiogenic switch, mediating vascularization and rapid expansion of the tumor. Elevated expression of NOX1 has been observed in the brain of Parkinson′s disease (PD) patients.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | mouse, human, bovine, canine |
| technique(s) | indirect ELISA: suitable,western blot: suitable |
| UniProt accession no. | Q9Y5S8 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... NOX1(27035) |
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¥ 1683.78
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¥ 2013.69
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¥ 20380.83
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