Anti-DDB2 antibody produced in rabbit,100UL,SAB5701000-100UL,Sigma

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订货号 0BP2985
品牌型号 Sigma SAB5701000-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]


Immunogen

A synthesized peptide derived from human DDB2


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, mouse
concentration0.4 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q92466
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... DDB2(1643)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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