AC253 trifluoroacetate salt,1MG,SML0625-1MG,Sigma

销售价: ¥ 3691.82 / 件
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订货号 0BP3346
品牌型号 Sigma SML0625-1MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

AC253 is an antagonist of Amylin, one of the peptides in the Calcitonin-gene related peptide (CGRP) family. In recent studies. AC253 restored memories in brain cells taken from animals used as models of Alzheimer′s disease. Application of AC253 significantly enhanced long-term potentiation (LTP) when given to 6- to 12-month-old TgCRND8 mice that normally show blunted LTP. In other studies, AC25 neutralized the depressant effects of Aβ(1-42) on hippocampal LTP without affecting baseline transmission or LTP on its own.
AC253 is an antagonist of Amylin.


Features and Benefits

This compound is featured on the Calcitonin Gene-Related Peptides page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


技术参数 Specifications
Quality Level100
assay≥95% (HPLC)
formpowder
color white to off-white
shipped inwet ice
storage temp.−20°C
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宽度(mm)
高度(mm)
重量(kg)
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