Anti-L1CAM antibody produced in rabbit,100UL,SAB5700268-100UL,Sigma

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订货号 0BP3510
品牌型号 Sigma SAB5700268-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1143-1257 of human L1CAM (NP_000416.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 138, 139, 140
species reactivitymouse, rat, human
concentration3.93 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.P32004
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... L1CAM(3897)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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