Anti-CD81 antibody produced in rabbit,100UG,SAB3501243-100UG,Sigma

销售价: ¥ 4150.58 / 件
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订货号 0BP5145
品牌型号 Sigma SAB3501243-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.


Immunogen

CD81 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human CD81.The immunogen is located within amino acids 30 - 80 of CD81.


Application

CD81 antibody can be used for detection of CD81 by Western blot at 2.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.


Physical form

Supplied in PBS containing 0.02% sodium azide.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivitymouse, rat, human
concentration1 mg/mL
technique(s)immunofluorescence: suitable,immunohistochemistry: suitable,western blot: suitable
isotypeIgG
NCBI accession no.NP_004347
UniProt accession no.P60033
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CD81(975)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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