Anti-C-Reactive Protein antibody produced in goat，2ML，C8284-2ML，Sigma

General description

C-reactive protein (CRP) is a first acute-phase plasma protein. It is synthesized in the hepatocyte and the concentration increase during inflammatory states even chronic inflammation. It′s level can increase during inflammation by up to 100 or 500 times.
C-reactive protein is encoded by the gene mapped to human chromosome 1q23.2.

Application

Anti-C-Reactive Protein antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA). It has also been used in immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
Anti-C-Reactive protein antibody has been used in:

• immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
• in-house ELISA assay to study the CRP levels in plasma sample.

Biochem/physiol Actions

C-reactive protein (CRP) plays an important role to provide an enhanced clearance of inappropriate materials from the plasma, whether these are of extrinsic origin, such as microorganisms and their products or the autologous products of cell damage and death. It acts as a systemic biomarker of acute inflammation and tissue damage.
Specificity for human CRP is determined by immunoelectrophoresis (IEP) versus human CRP positive serum and purified human CRP. No reactivity with normal human serum is observed.

Physical form

Goat Anti-Human CRP is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative.

Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.