Anti- NF2 antibody produced in rabbit,100UL,SAB5701057-100UL,Sigma

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订货号 0BP6351
品牌型号 Sigma SAB5701057-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 477-576 of human NF2 (NP_000259.1).


Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivitymouse, rat, human
concentration6.49 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P35240
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... NF2(4771)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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