Anti-SF3B3/SAP130 antibody produced in rabbit,100UL,SAB5701704-100UL,Sigma

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订货号 0BP6865
品牌型号 Sigma SAB5701704-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]


Immunogen

A synthesized peptide derived from human SF3B3/SAP130


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityrat, mouse, human
concentration0.9 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q15393
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SF3B3(23450)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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