Anti-Interleukin-11 antibody produced in goat，1MG，I5270-1MG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Rα and gp130Rβ subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation
Anti-Interleukin-11 antibody specifically reacts with human IL-11.

Immunogen

recombinant human IL-11 expressed in Sf 21 insect cells.

Application

Anti-Human IL-11 is suitable for neutralization reactions.

Biochem/physiol Actions

The antibody neutralizes the biological activity of recombinant human IL-11.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	goat
Quality Segment	100
conjugate	unconjugated
antibody form	IgG fraction of antiserum
antibody product type	primary antibodies
clone	polyclonal
form	lyophilized powder
species reactivity	human
technique(s)	neutralization: suitable
UniProt accession no.	P20809
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... IL11(3589)

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