- 商品介绍
- 规格参数
- 包装参数
General description
Hepatitis C virus core antigen (HCV-cAg) is a well-preserved antigenic protein of the internal capsid.
Hepatitis C virus glycoprotein 1 (HCVgp1), also referred to as polyprotein, is crucial for the induction of double-membrane vesicles, sites of HCV RNA amplification. The amino terminal of polyprotein contains the structural proteins core, envelope protein 1 (E1) and E2. The proteolytic cleavage of polyprotein results in the formation of 10 mature viral proteins which are needed for viral replication and assembly.
amino acids 2-192 of HCV polyprotein
Application
Hepatitis core antigen (HCA) has been used as an analyte in enzyme-linked immunosorbent assay (ELISA) to study the mechanism of bovine serum albumin (BSA) blocking in common ELISA protocols.
Biochem/physiol Actions
Hepatitis C virus core antigen (HCV-cAg) may be a less expensive way to diagnose active hepatitis C virus (HCV) infection in the hemodialysis (HD) population.
Positive control for HCV antibodies.
Reacts strongly with human HCV positive serum.
Physical form
Solution in 8 M Urea, 20 mM Tris-HCl, pH 8.0, 10 mM 2-mercaptoethanol.
Other Notes
HCV core antigen [2-192]-Galactosidase-tagged at the N-terminus.
| recombinant | expressed in E. coli |
| Quality Segment | 200 |
| assay | ≥95% (SDS-PAGE) |
| mol wt | 22 kDa (plus 114 kDa galactosidse) |
| concentration | ~1 mg/mL |
| UniProt accession no. | G9G988,L7S4V3 |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | hepatitis C virus ... HCVgp1(951475) human ... HBVgp4(944568) |
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¥ 2019.57
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¥ 9207.92
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¥ 4039.86
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¥ 745.60
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¥ 4020.77
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¥ 787.34
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¥ 1351.48
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¥ 954.17
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¥ 4476.05
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¥ 145427.01
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¥ 26846.31
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¥ 99441.38
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¥ 52185.37
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