Anti-WNT3 antibody produced in rabbit，100UL，SAB2105736-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

Immunogen

Synthetic peptide directed towards the middle region of human WNT3

Biochem/physiol Actions

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: SHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNE

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	37 kDa
species reactivity	bovine, rat, human, guinea pig, rabbit, dog, horse, mouse
concentration	0.5 mg - 1 mg/mL
technique(s)	western blot: suitable
NCBI accession no.	NM_030753
UniProt accession no.	P56703
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... WNT3(7473)

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