Monoclonal Anti-CD73 FITC produced in mouse，100YL4，SAB4702008-100TST，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.

Immunogen

pre-B leukemia cells

Biochem/physiol Actions

The mouse monoclonal antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on the surface of T and B cell subsets, follicular dendritic cells and endothelial cells.

Physical form

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preparation Note

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

技术参数 Specifications

conjugate	FITC conjugate
Quality Segment	100
antibody product type	primary antibodies
clone	AD2, monoclonal
form	buffered aqueous solution
species reactivity	( Non-human primates), human
technique(s)	flow cytometry: suitable
isotype	IgG1κ
UniProt accession no.	P21589
storage temp.	2-8°C
target post-translational modification	unmodified
Gene Information	human ... NT5E(4907)

长度(mm)
宽度(mm)
高度(mm)
重量(kg)