Anti-TNFR2/TNFRSF1B Antibody, clone 7S1K0, Rabbit Monoclonal,100UL,SAB5702091-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BP9153
品牌型号 Sigma SAB5702091-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 362-461 of human TNFR2/TNFRSF1B (P20333).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone7S1K0, monoclonal
formliquid
mol wt 68 kDa
species reactivityhuman, rat
concentration0.38 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceRASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
UniProt accession no.P20333
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TNFRSF1B(7133)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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