Monoclonal Anti-Peroxisome Proliferator Activated Receptor α antibody produced in mouse，100UG，P0869-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.

Immunogen

purified recombinant PPARα protein.

Biochem/physiol Actions

Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.

Physical form

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Segment	200
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	3B6/PPAR, monoclonal
form	buffered aqueous solution
species reactivity	mouse, rat, human
concentration	~1 mg/mL
technique(s)	western blot: 2-5 μg/mL using human, mouse and rat
isotype	IgG2b
UniProt accession no.	Q07869
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... PPARA(5465) mouse ... Ppara(19013) rat ... Ppara(25747)

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