Anti-SPANXB1 antibody produced in mouse,50UG,SAB1402100-50UG,Sigma

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订货号 0BQ0269
品牌型号 Sigma SAB1402100-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. (provided by RefSeq)


Immunogen

SPANXB1 (NP_115850.1, 1 a.a. ~ 103 a.a) full-length human protein.

Sequence
MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSPEELVNDHARENRINPDQMEEEEFIEITTERPKK


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)direct immunofluorescence: suitable,western blot: 1 μg/mL
NCBI accession no.NM_032461.2
UniProt accession no.Q9NS25
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SPANXB1(728695)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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