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General description
Interleukin-23 (IL-23) is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3.
The IL23A ELISA kit provides for the Quantitative measurement of IL-23 in Cell Culture Supernatants, Plasma and Serum.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Interleukin-23 (IL-23) plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type cell culture supernatant(s) sample type serum sample type plasma |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 25 pg/mL standard curve range: 28.67-7000 pg/mL |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... IL23A(51561) |
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